1. An uneasy feeling arising from conscience or principle that tends to hinder action.

2. A unit of apothecary weight equal to about 1.3 grams, or 20 grains.

3. A minute part or amount.

4. Doubt or uncertainty regarding a question of moral right or duty.

5. A feeling of uncertainty about the fitness or correctness of an action.

6. Motivation deriving logically from ethical or moral principles that govern a person's thoughts and actions.
 

1. Writing is conscience, scruple, and the farming of our ancestors.

2. Let us not scruple to employ the weapons of ridicule and sarcasm in defense of free speech and reason.

3. The Count's scruples might have been honourable and reasonable enough, but there was something in his manner of expressing them which increased my unwillingness to be concerned in the business of the signature.

crumb, dab, dash, dot, dram, drop, fragment, grain, iota, jot, minim, mite, modicum, molecule, ort, ounce, particle, scrap, shred, smidgen, speck, tittle, trifle, whit, scruple